2(S)-amino-6-boronohexanoic acid

Ligand id: 5107

Name: 2(S)-amino-6-boronohexanoic acid

Abbreviated name: ABH

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 4
Rotatable bonds 6
Topological polar surface area 103.78
Molecular weight 175.1
XLogP -2.85
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
Arginase I Hs Inhibitor Inhibition 8.3 pKd - 1
pKd 8.3 (Kd 5x10-9 M) [1]
Arginase II Hs Inhibitor Inhibition 8.1 pKi - 2
pKi 8.1 (Ki 8.5x10-9 M) [2]
Ligand mentioned in the following text fields