Ligand id: 6927

Name: ABT-288

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 3
Topological polar surface area 26.79
Molecular weight 372.2
XLogP 4.4
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Bioactivity Comments
ABT-288 is a selective and potent H3R antagonist with broad procognitive efficacy in rodents and excellent drug-like properties [1]