zonisamide

Ligand id: 7047

Name: zonisamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 94.57
Molecular weight 212.03
XLogP 1.03
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
As the precise MMOA for this drug is unclear we have not tagged a primary drug target.
Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
carbonic anhydrase 1 Hs Inhibitor Inhibition 7.3 pKi - 1
pKi 7.3 (Ki 5.6x10-8 M) [1]
carbonic anhydrase 7 Hs Inhibitor Inhibition 6.9 pKi - 1
pKi 6.9 (Ki 1.17x10-7 M) [1]
carbonic anhydrase 12 Hs Inhibitor Inhibition 5.0 pKi - 1
pKi 5.0 (Ki 1.1x10-5 M) [1]