BMS-599626

Ligand id: 7647

Name: BMS-599626

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 3
Rotatable bonds 9
Topological polar surface area 119.63
Molecular weight 530.22
XLogP 2.69
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human catalytic receptors
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
epidermal growth factor receptor Inhibitor Inhibition 7.5 pIC50 - 1
pIC50 7.5 (IC50 3.2x10-8 M) [1]
erb-b2 receptor tyrosine kinase 2 Inhibitor Inhibition 7.5 pIC50 - 1
pIC50 7.5 (IC50 2.2x10-8 M) [1]
erb-b2 receptor tyrosine kinase 4 Inhibitor Inhibition 6.7 pIC50 - 1
pIC50 6.7 (IC50 1.9x10-7 M) [1]