Ligand id: 7848

Name: CGP13501

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 37.3
Molecular weight 290.22
XLogP 6.13
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
CGP13501 significantly increases GABA-induced GTP&gamma'[35S] binding to CHO cell membranes containing human GABAB1 and rat GABAB2 subunits [1].