compound 20 [PMID: 22136433]

Ligand id: 8156

Name: compound 20 [PMID: 22136433]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 0
Topological polar surface area 69.85
Molecular weight 362.07
XLogP 1.24
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Pim-1 proto-oncogene, serine/threonine kinase Inhibitor Inhibition 7.2 pIC50 - 1
pIC50 7.2 (IC50 6x10-8 M) [1]
Calmodulin-dependent kinase II Inhibitor Inhibition 7.1 pIC50 - 1
pIC50 7.1 (IC50 8.3x10-8 M) [1]
Pim-3 proto-oncogene, serine/threonine kinase Inhibitor Inhibition 7.1 pIC50 - 1
pIC50 7.1 (IC50 9x10-8 M) [1]
protein kinase N1 Inhibitor Inhibition 6.5 pIC50 - 1
pIC50 6.5 (IC50 3.1x10-7 M) [1]