compound 3 [PMID: 19097791]

Ligand id: 8185

Name: compound 3 [PMID: 19097791]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 93.3
Molecular weight 454.21
XLogP 3.71
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
protein kinase C zeta Hs Inhibitor Inhibition 8.6 pIC50 - 1
pIC50 8.6 (IC50 2.26x10-9 M) [1]
cyclin dependent kinase 2 Hs Inhibitor Inhibition 8.4 pIC50 - 1
pIC50 8.4 (IC50 4.1x10-9 M) [1]