bromosporine

Ligand id: 8234

Name: bromosporine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 135.96
Molecular weight 404.13
XLogP 2.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Bioactivity Comments
Differential scanning fluorimetry (DSF) data on the Structural Genomics Consortium's (SGC) website indicates that bromosporine inhibits BRD-containing proteins including BRD2, BRD3, BRD4, BRD9, BRDT and CECR2 [1].