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Synonyms: BA058 | Tymlos®
abaloparatide is an approved drug (FDA (2017))
Compound class:
Peptide or derivative
Comment: Abaloparatide is a synthetic analogue of the 34 amino-terminal residues of human parathyroid hormone-related protein (PTHrP) [1]. Compare this to the approved drug teriparatide which is a synthetic analogue of human parathyroid hormone (PTH). Abaloparatide and teriparatide are synthetic peptides that help grow and strengthen bone.
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| Bioactivity Comments |
| As this is an analogue of an endogenous peptide we have tagged its primary target as the PTH1 receptor, although we have been unable to find affinity data for the peptide-receptor interaction. |
| Selectivity at GPCRs | ||||||||||||||||||||||||||||||||||
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