compound 1 [PMID: 25719566]

Ligand id: 8302

Name: compound 1 [PMID: 25719566]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 5
Topological polar surface area 72.32
Molecular weight 354.16
XLogP 4.83
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human other protein targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
bromodomain adjacent to zinc finger domain 2B Inhibitor Inhibition 4.6 pIC50 - 1
pIC50 4.6 (IC50 2.6x10-5 M) [1]