Ligand id: 8401

Name: evacetrapib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 1
Rotatable bonds 9
Topological polar surface area 87.38
Molecular weight 638.28
XLogP 8.25
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Bioactivity Comments
Evacetrapib inhibits CETP in human plasma with an IC50 value of 26nM [1].