AZD2858

Ligand id: 8478

Name: AZD2858

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 10
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 142.79
Molecular weight 453.16
XLogP 0.96
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
glycogen synthase kinase 3 beta Inhibitor Inhibition 8.3 pKi - 1
pKi 8.3 (Ki 4.9x10-9 M) [1]