Ligand id: 8707

Name: deutetrabenazine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 38.77
Molecular weight 317.2
XLogP 2.69
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

Bioactivity Comments
The inhibitory ability of deutetrabenazine is likely to be similar to that of its parent compound, tetrabenazine. We have mapped deutetrabenazine to SLC18A2, based on its relationship to the parent molecule, but have been unable to find confirmatory activity data.
Selectivity at transporters
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Target Sp. Type Action Affinity Units Concentration range (M) Reference
Vesicular monoamine transporter 2 Hs Inhibitor Inhibition - - -