RBM2-1B

Ligand id: 8879

Name: RBM2-1B

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 23
Topological polar surface area 74.63
Molecular weight 427.35
XLogP 10.05
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at enzymes
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Value Parameter Concentration range (M) Reference
delta 4-desaturase, sphingolipid 1 Hs Inhibitor Inhibition 4.7 pIC50 - 1
pIC50 4.7 (IC50 1.81x10-5 M) [1]
Description: Measured in a A549 cellular assay as the formation of CerC6NBD from dihydro CerC6NBD.