BAY-598

Ligand id: 8953

Name: BAY-598

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 8
Hydrogen bond donors 2
Rotatable bonds 10
Topological polar surface area 113.55
Molecular weight 524.09
XLogP 4.04
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
SET and MYND domain containing 2 Inhibitor Inhibition 7.6 pIC50 - 2
pIC50 7.6 (IC50 2.7x10-8 M) [2]
Description: Measuring inhibition of methylation of p53K370 in vitro