sauvagine   Click here for help

GtoPdb Ligand ID: 918

Comment: Isolated from the skin of the Sauvage's leaf frog (Phyllomedusa sauvagei)
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Selectivity at GPCRs
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Target Sp. Type Action Value Parameter Concentration range (M) Reference
CRF2 receptor Mm Agonist Full agonist 8.4 – 8.7 pKd - 4-6
pKd 8.4 – 8.7 [4-6]
CRF2 receptor Hs Agonist Full agonist 7.6 – 9.3 pKd - 2-3
pKd 7.6 – 9.3 [2-3]
CRF2 receptor Rn Agonist Full agonist 8.0 – 8.8 pKd - 4-5
pKd 8.0 – 8.8 [4-5]
CRF1 receptor Hs Agonist Full agonist 6.7 – 9.2 pKd - 1-6
pKd 6.7 – 9.2 [1-6]