BIIB021

Ligand id: 9258

Name: BIIB021

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 3
Topological polar surface area 91.74
Molecular weight 318.1
XLogP 1.1
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human enzymes
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
coactivator associated arginine methyltransferase 1 Inhibitor Inhibition >8.0 pIC50 - 2
pIC50 >8.0 (IC50 <1x10-8 M) [2]
Description: In vitro methylation of H3 (1-25).
Selectivity at human other protein targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
heat shock protein 90 alpha family class A member 1 Inhibitor Inhibition 8.7 pIC50 - 1
pIC50 8.7 (IC50 2x10-9 M) [1]