Ligand id: 9474

Name: encaleret

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 78.79
Molecular weight 513.21
XLogP 8.05
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from GtoPdb and ChEMBL (where available) across species

Selectivity at GPCRs
Key to terms and symbols Click column headers to sort
Target Sp. Type Action Affinity Units Concentration range (M) Reference
CaS receptor Hs Allosteric modulator Negative 7.9 pIC50 - 1
pIC50 7.9 [1]
Description: Inhibition of 5 mM Ca2+-mediated luciferase reporter activity