encaleret

Ligand id: 9474

Name: encaleret

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 11
Topological polar surface area 78.79
Molecular weight 513.21
XLogP 8.05
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at human GPCRs
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Target Type Action Affinity Units Concentration range (M) Reference
CaS receptor Allosteric modulator Negative 7.9 pIC50 - 1
pIC50 7.9 [1]
Description: Inhibition of 5 mM Ca2+-mediated luciferase reporter activity