Compound 34c [PMID 24641010]

Ligand id: 9647

Name: Compound 34c [PMID 24641010]

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 5
Topological polar surface area 106.24
Molecular weight 423.17
XLogP 3.89
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

View interactive charts of activity data from ChEMBL and GtoPdb across species (New!)

Selectivity at plasmodium falciparum other protein targets
Key to terms and symbols Click column headers to sort
Target Type Action Affinity Units Concentration range (M) Reference
Plasmodium falciparum N-Myristoyltransferase Inhibitor Inhibition 8.1 pKi - 2
pKi 8.1 (Ki 8x10-9 M) The parasite EC50 against Pfal was 305 nM [2]