baclofen

Ligand id: 1084

Name: baclofen

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 63.32
Molecular weight 213.06
XLogP 1.58
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
This skeletal muscle relaxant is used to reduce the frequency of muscle spasms and muscle spasticity associated with spinal chord injury.
Mechanism Of Action and Pharmacodynamic Effects
Baclofen is a GABAB receptor agonist. Activation of these receptors produces baclofen's range of therapeutic actions.