(R)-cetirizine

Ligand id: 1214

Name: (R)-cetirizine

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View more information in the IUPHAR Pharmacology Education Project: levocetirizine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 8
Topological polar surface area 53.01
Molecular weight 388.16
XLogP 4.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Levocetirizine is used to treat symptoms of perennial and seasonal allergies, and chronic (idiopathic) urticaria.
Mechanism Of Action and Pharmacodynamic Effects
Blocks the activity of histamine at the histamine H1 receptor.