Synonyms: sulfathiocarbamide
Compound class:
Synthetic organic
Comment: Sulfathiourea is a short-acting sulfonamide antibacterial compound.
|
|
No information available. |
Mechanism Of Action and Pharmacodynamic Effects |
Sulfonamides are structural analogues of 4-aminobenzoic acid (pABA) an intermediate in the de novo synthesis of folate by some prokaryotes, lower eukaryotes and plants [2]. The antibacterial MMOA is competitive inhibition of bacterial dihydropteroate synthase (DHPS) resulting in a block of folate biosynthesis [1]. |