Synonyms: BVL-GSK098
Compound class:
Synthetic organic
Comment: Alpibectir is being developed by BioVersys AG and GlaxoSmithKline as an oral treatment for tuberculosis (TB) in combination with ethionamide or prothionamide. Alpibectir targets bacterial transcriptional regulators and potentiates the activity of drugs used in the treatment of TB, in particular drugs that are activatable via the EthA pathway. It is one of the spiroisoxazoline class of compounds claimed in patent WO2019034700A1 [1].
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Clinical Trials | |||||
Clinical Trial ID | Title | Type | Source | Comment | References |
NCT05473195 | A Phase 2 Trial to Evaluate the EBA, Safety and Tolerability of Eto Alone and in Combination With BVL-GSK098 | Phase 2 Interventional | TASK Applied Science | ||
NCT04654143 | Clinical Trial to Investigate the Safety, Tolerability and Pharmacokinetics of BVL-GSK098 in Healthy Volunteers | Phase 1 Interventional | BioVersys AG |