Ligand id: 148

Name: ergometrine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 68.36
Molecular weight 325.18
XLogP 0.87
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
This drug is used to stem uterine bleeding post-partum or following abortion. However, there is no information regarding marketing approval for this drug on the US FDA or European Medicines Agency websites, other than to note that approval is granted by individual national agencies.
Mechanism Of Action and Pharmacodynamic Effects
This drug appears to have multiple molecular targets, including adrenoceptors, dopamine receptors, and 5-HT receptors, although the exact mechanism of action remains unclear.