Ligand id: 1629

Name: nalorphine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 52.93
Molecular weight 311.15
XLogP 1.41
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Previously used to reverse opioid overdose and in a challenge test to determine opioid dependence.
Mechanism Of Action and Pharmacodynamic Effects
μ opioid receptor antagonist, κ receptor agonist.