Ligand id: 205

Name: loxapine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 0
Rotatable bonds 1
Topological polar surface area 28.07
Molecular weight 327.11
XLogP 4.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Antipsychotic used in the management of schizophrenia and bipolar idsorder.
Mechanism Of Action and Pharmacodynamic Effects
The exact mechanism of action of loxapine is unknown, however, it is known to be a antagonist of dopamine and 5-HT2 receptors.