vitamin D3

Ligand id: 2747

Name: vitamin D3

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 1
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 20.23
Molecular weight 384.34
XLogP 9.9
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of vitamin D deficiency, refractory rickets, familial hypophosphatemia and hypoparathyroidism.
Mechanism Of Action and Pharmacodynamic Effects
For an overview of the mechanism of action of vitamin D3, please see the DrugBank link on the Summary tab of this ligand page. We have not tagged a primary target for this drug as we have been unable to find affinity data for this drug (at the human target) to substantiate its binding to the vitamin D receptor (VDR).