paricalcitol

Ligand id: 2791

Name: paricalcitol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 3
Rotatable bonds 5
Topological polar surface area 60.69
Molecular weight 416.33
XLogP 6.14
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of secondary hyperparathyroidism associated with chronic kidney disease.
Mechanism Of Action and Pharmacodynamic Effects
Binding of the vitamin D receptor by paricalcitol results in activation of vitamin D responsive pathways.
External links