Ligand id: 2895

Name: parecoxib

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 97.65
Molecular weight 370.1
XLogP 4.63
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Approved for short term perioperative pain control.
Mechanism Of Action and Pharmacodynamic Effects
Parecoxib is a cyclooxygenase 2 (COX-2) selective inhibitor. It therefore interferes with the production of pro-inflammatory prostaglandins.
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