Ligand id: 2897

Name: lumiracoxib

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 2
Rotatable bonds 4
Topological polar surface area 49.33
Molecular weight 293.06
XLogP 4.31
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
A non-steroidal anti-inflammatory drug that has been used in the treatment of osteoarthritis. Withdrawn from use in the EU, Canada, Australia, and New Zealand, lumiracoxib is still used clinically in several countries in Central and South America.
Mechanism Of Action and Pharmacodynamic Effects
Inhibitor of COX-2, leading to the inhibition of prostaglandin synthesis.