bethanechol

Ligand id: 297

Name: bethanechol

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 4
Topological polar surface area 52.32
Molecular weight 161.13
XLogP -0.52
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Bethanechol increases smooth muscle tone, and can be used following abdominal surgery to promote GI tract motility or to promote bladder function in patients with non-bostrictive urinary retention.
Mechanism Of Action and Pharmacodynamic Effects
The predominantly muscarinic actions of bethanechol directly stimulate cholinergic receptors in the parasympathetic nervous system.