Ligand id: 4002

Name: vecuronium

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 55.84
Molecular weight 557.43
XLogP 6.78
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used as a muscle-relaxing agent and as an adjuct in general anaesthesia.
Mechanism Of Action and Pharmacodynamic Effects
Competitively binds nicotinic acetylcholine receptors, decreasing the binding of acetylcholine at the postjunctional membrane of the myoneural junction. This prevents depolarisation and the release of calcium ions and therefore muscle contraction does not occur.
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