Summary of Clinical Use

Used as a muscle-relaxing agent and as an adjuct in general anaesthesia.

Mechanism Of Action and Pharmacodynamic Effects

Competitively binds nicotinic acetylcholine receptors, decreasing the binding of acetylcholine at the postjunctional membrane of the myoneural junction. This prevents depolarisation and the release of calcium ions and therefore muscle contraction does not occur.

External links

For extended ADME data see the following: Electronic Medicines Compendium (eMC) Drugs.com