Ligand id: 4003

Name: rocuronium

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 59
Molecular weight 529.4
XLogP 5.03
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used as an adjunct to general anaesthesia to enable rapid sequence and routine tracheal intubation, and to provide skeletal muscle relaxation during surgery or mechanical ventilation.
Mechanism Of Action and Pharmacodynamic Effects
Causes a decreased response to acetylcholine at the neuromuscular junction of skeletal muscle by competing with the binding of the neurotransmitter at cholinergic receptors. This results in muscle relaxation.
External links