Ligand id: 4242

Name: lubiprostone

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View more information in the IUPHAR Pharmacology Education Project: lubiprostone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 2
Rotatable bonds 11
Topological polar surface area 83.83
Molecular weight 390.22
XLogP 4.31
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of chronic constipation and irritable bowel syndrome.
Mechanism Of Action and Pharmacodynamic Effects
For an overview of the mechanism of action of lubiprostone, please see the entry on DrugBank linked to from this ligand page.