zaleplon

Ligand id: 4345

Name: zaleplon

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 0
Rotatable bonds 4
Topological polar surface area 74.29
Molecular weight 305.13
XLogP 2.21
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the short-term treatment of insomnia.
Mechanism Of Action and Pharmacodynamic Effects
Induces subunit modulation of the GABAA receptor. Also potentiates t-butyl-bicyclophosphorothionate (TBPS) binding to the brain omega-1 receptor located on the alpha subunit of the GABA-A/chloride ion channel receptor complex.
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