Ligand id: 4716

Name: valganciclovir

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 11
Hydrogen bond donors 5
Rotatable bonds 9
Topological polar surface area 166.75
Molecular weight 355.17
XLogP -1.68
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Antiviral medication used in the treatment of cytomegalovirus infections-in immuno-compromised patients (eg those with AIDS) or in patients who have received a solid organ transplant from a CMV-positive donor.
Mechanism Of Action and Pharmacodynamic Effects
Prodrug of ganciclovir, the phosphorylation products of which inhibit viral DNA synthesis.
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