estrone-3-sulphate

Ligand id: 4749

Name: estrone-3-sulphate

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 1
Rotatable bonds 2
Topological polar surface area 89.05
Molecular weight 350.12
XLogP 2.74
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Estropipate is used to treat post-menopausal symptoms arising from estrogen deficiency (such as vaginal atrophy and osteoporosis), as well as some estrogen responsive breast and prostate cancers.
Mechanism Of Action and Pharmacodynamic Effects
Acts like estradiol, via estrogen receptor α, to regulate transcription of genes containing estrogen response elements.