Ligand id: 4797

Name: mazindol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 3
Hydrogen bond donors 1
Rotatable bonds 1
Topological polar surface area 35.83
Molecular weight 284.07
XLogP 4.5
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the short term treatment of exogenous obesity.
Mechanism Of Action and Pharmacodynamic Effects
The exact mechanism of action of mazindol as an obesity treatment is unknown; however, it is believed to inhibit the reuptake of noradrenaline.