procainamide

Ligand id: 4811

Name: procainamide

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 7
Topological polar surface area 58.36
Molecular weight 235.17
XLogP 1.49
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of ventricular arrhythmias.
Mechanism Of Action and Pharmacodynamic Effects
Procainamide causes local anesthetic action by stabilising the neuronal membrane. This is achieved by blocking sodium channel-induced ionic fluxes. Such ionic conductance is required for the normal initiation and transmission of nerve impulses.
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