didanosine

Ligand id: 4833

Name: didanosine

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 7
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 88.41
Molecular weight 237.1
XLogP -0.71
No. Lipinski's rules broken 0

Molecular properties generated using the CDK
No information available.
Summary of Clinical Use
Didanosine is used as a component of combination antiretroviral therapy to treat HIV-1 infection.
Mechanism Of Action and Pharmacodynamic Effects
Didanosine inhibits the reverse transcriptase of HIV-1, preventing further viral replication.