ceftriaxone

Ligand id: 5326

Name: ceftriaxone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 13
Hydrogen bond donors 5
Rotatable bonds 9
Topological polar surface area 287.49
Molecular weight 555.05
XLogP -2.69
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat bacterial infections.
Mechanism Of Action and Pharmacodynamic Effects
Ceftriaxone works by inhibiting synthesis in the bacterial cell wall and in addition, binds to carboxypeptidases, endopeptidases, and transpeptidases (enzymes involved in cell-wall synthesis and cell division) in the bacterial cytoplasmic membrane. Ceftriaxone results in the formation of defective cell walls and cell death.