Ligand id: 550

Name: bupranolol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 2
Rotatable bonds 6
Topological polar surface area 41.49
Molecular weight 271.13
XLogP 3.01
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of hypertension and tachycardia and in the management of glaucoma. Bupranolol does not appear to have marketing approval in the US or EU, although individual countries may have approved use of this drug.
Mechanism Of Action and Pharmacodynamic Effects
Bupranolol reduces resting heart rate, cardiac output, and blood pressure by inhibiting sympathetic stimulation arising from β1-adrenergic receptor activation in the heart.