sufinpyrazone

Ligand id: 5826

Name: sufinpyrazone

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 5
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 76.9
Molecular weight 404.12
XLogP 4.96
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to reduce the serum urate levels in patients with gout. The marketing authorisation for Anturane® in the US has been discontinued.
Mechanism Of Action and Pharmacodynamic Effects
Competitively inhibits reabsorption of uric acid at the proximal convoluted tubul, facilitating urinary excretion of uric acid and decreasing plasma urate concentrations.