clemastine

Ligand id: 6063

Name: clemastine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 2
Hydrogen bond donors 0
Rotatable bonds 6
Topological polar surface area 12.47
Molecular weight 343.17
XLogP 6.51
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to treat hay fever, rhinitis, allergic skin conditions, and pruritus
Mechanism Of Action and Pharmacodynamic Effects
The drug blocks the action of endogenous histamine at the histamine H1 receptor.
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