deoxycholic acid

Ligand id: 610

Name: deoxycholic acid

Abbreviated name: DCA

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 4
Topological polar surface area 77.76
Molecular weight 392.29
XLogP 5.76
No. Lipinski's rules broken 1

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Deoxycholic acid under the brand name Kybella is approved to reduce the accumulated fat cells causing submental fullness, aka 'double chin'. Kybella should not be used outside of the submental area.
Mechanism Of Action and Pharmacodynamic Effects
Deoxycholic acid causes cytolysis of cells at the site of injection, so killing fat cells which injected correctly under the skin. The compound will kill other cells types if injected into the wrong tissue.