Ligand id: 6286

Name: sitagliptin

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 6
Hydrogen bond donors 1
Rotatable bonds 6
Topological polar surface area 77.04
Molecular weight 407.12
XLogP 2.81
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used in the treatment of type 2 diabetes.
Mechanism Of Action and Pharmacodynamic Effects
For an overview of the mechanism of action of sitagliptin, please see the DrugBank entry linked to from this ligand page.
External links