deslanoside

Ligand id: 6806

Name: deslanoside

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 19
Hydrogen bond donors 9
Rotatable bonds 10
Topological polar surface area 282.21
Molecular weight 942.48
XLogP 0.64
No. Lipinski's rules broken 2

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to manage congestive cardiac insufficiency, arrhythmias and heart failure. According to the US FDA International Drugs listing, this drug is only available in Brazil, China and Japan.
Mechanism Of Action and Pharmacodynamic Effects
This cardiotonic glycoside inhibits the Na-K-ATPase membrane pump, resulting in an increase in intracellular sodium and calcium concentrations.