Ligand id: 6808

Name: dicumarol

Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 2
Rotatable bonds 2
Topological polar surface area 93.06
Molecular weight 336.06
XLogP 3.67
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Until the the mid-1950s, this compound was used as a medicinal anticoagulant drug. This was replaced by its simpler derivative warfarin, and other 4-hydroxycoumarin drugs
Mechanism Of Action and Pharmacodynamic Effects
An oral anticoagulant that interferes with the metabolism of vitamin K; of combined plant and fungal origin