famotidine

Ligand id: 7074

Name: famotidine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 9
Hydrogen bond donors 4
Rotatable bonds 7
Topological polar surface area 237.75
Molecular weight 337.04
XLogP -1.16
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Famotidine is used to treat stomach and duodenal ulcers, gastroesophageal reflux, and conditions of over-production of stomach acid.
Mechanism Of Action and Pharmacodynamic Effects
Famotidine is a histamine H2 antagonist. Activation of this receptor mediates gastric acid secretion, so antagonism inhibits gastric acid secretion.
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