Ligand id: 7117

Name: apraclonidine

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Structure and Physico-chemical Properties

2D Structure
Calculated Physico-chemical Properties
Hydrogen bond acceptors 4
Hydrogen bond donors 3
Rotatable bonds 2
Topological polar surface area 62.44
Molecular weight 244.03
XLogP 1.37
No. Lipinski's rules broken 0

Molecular properties generated using the CDK

No information available.
Summary of Clinical Use
Used to reduce intraocular pressure.
Mechanism Of Action and Pharmacodynamic Effects
An agonist of α2-adrenoceptors, believed to decrease aqueous humor production and increase uveo-scleral outflow, thus reducing overall intraocular pressure.
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